The Isozaki Towers are symbols of the urbanistic transformation that is taking place in Bilbao. They are built close to the commercial and historic centres of the city along the river bank. Practically all of the old industrial areas along the river bank have been redeveloped and modernised with residential buildings and offices.
Directly opposite the modern tower buildings sit some traditional residential buildings. They certainly don't seem to be overshadowed by their modern counterparts. I suppose that, as with everything, it is merely a question of taste.